Hyderabad hospital introduces South India's first ZAP-X system for non-invasive brain tumour treatment

Mar 06, 2026

Hyderabad (Telangana) [India], March 6 : The AIG Hospitals today announced the launch of the ZAP-X Gyroscopic Neuro-Radiosurgery Platform, the first installation of its kind in South India and only the second in the country, marking a major advancement in the treatment of brain tumours and complex neurological disorders.
Designed exclusively for intracranial radiosurgery, ZAP-X enables doctors to treat brain lesions with extreme precision without open surgery, without incisions, and as a day-care procedure, according to an official release.
The system delivers highly focused radiation beams with sub-millimetre accuracy, targeting tumours and abnormal tissues while sparing healthy brain structures. For patients, this means a completely non-invasive treatment that is painless, requires no hospital stay, and allows them to return to normal life quickly.
Brain tumours and related neurological disorders represent a growing health burden in India. Traditionally, many of these conditions have required complex neurosurgery involving craniotomy, prolonged hospitalisation, and significant recovery time.
Stereotactic radiosurgery has emerged globally as a safer alternative for carefully selected cases, and the introduction of ZAP-X at AIG Hospitals brings one of the world's most advanced neuro-radiosurgical technologies to patients across South India.



Speaking on the occasion, D. Nageshwar Reddy, Chairman, AIG Hospitals, said, "At AIG Hospitals, our vision has always been to bring the most advanced medical technologies to patients in a manner that makes high-quality care both accessible and patient-centric. The introduction of the ZAP-X Gyroscopic Radiosurgery Platform represents a major step in that direction. Conditions that once required complex brain surgery can now be treated with extraordinary precision, as a day-care procedure and without a single incision. For patients and families, this means less trauma, faster recovery, and renewed hope. We believe this technology will significantly benefit patients across Telangana, Andhra Pradesh, and neighbouring regions, while further strengthening Hyderabad's position as a centre of excellence for advanced neurological care."
The ZAP-X platform is designed to treat a wide range of intracranial conditions, including benign and malignant brain tumours, brain metastases, arteriovenous malformations (AVMs), trigeminal neuralgia, and other complex neurological disorders.
Highlighting the clinical scope of the technology, Subodh Raju, Director & Head - Neurosurgery, AIG Hospitals, said, "Modern neurosurgery increasingly focuses on precision and minimal invasiveness. With ZAP-X, we are able to treat several brain conditions that previously required open surgery or complex radiotherapy protocols. This includes benign tumours such as meningiomas and acoustic neuromas, malignant tumours, vascular malformations, and severe facial pain conditions like trigeminal neuralgia. AIG Hospitals has built a strong multidisciplinary ecosystem involving neurosurgeons, radiation oncologists, neuroradiologists, and medical physicists, ensuring that each patient receives a carefully coordinated treatment plan. Our goal is to deliver the best possible outcomes while preserving neurological function and quality of life."
One of the areas where ZAP-X is expected to make a particularly significant impact is in the treatment of brain metastases, tumours that spread to the brain from cancers elsewhere in the body, most commonly from the lung, breast, or melanoma.
Brain metastases are among the most common brain tumours worldwide. Traditionally, treatment options have included open surgery or whole-brain radiation therapy, which can expose large areas of the brain to radiation and may lead to side effects affecting cognition and quality of life. In contrast, ZAP-X allows doctors to target only the tumor deposits with extreme precision, minimizing radiation exposure to healthy brain tissue.
Studies have shown that this focused approach can significantly improve outcomes, especially for patients who may have multiple small metastases, allowing them to receive effective treatment without the need for invasive surgery or prolonged hospital stays.
John R. Adler, renowned neurosurgeon, inventor of CyberKnife and ZAP-X, and one of the world's foremost pioneers in radiosurgery, emphasised the broader potential of the technology,
"Radiosurgery has evolved tremendously over the past three decades, and ZAP-X represents the next generation of this field. While brain tumours remain a primary indication, the precision of this technology also opens up exciting possibilities in the treatment of functional neurological conditions such as trigeminal neuralgia, movement disorders, and now, we are seeing trials to treat depression as well. The goal has always been to treat disease with surgical accuracy but without the invasiveness of traditional surgery. It is gratifying to see institutions like AIG Hospitals bringing this level of innovation to patients in India," he said
The installation of ZAP-X at AIG Hospitals also reinforces Hyderabad's growing reputation as a hub for advanced healthcare technology and medical innovation, offering patients access to world-class treatment closer to home.
With its ability to treat complex brain conditions through precise, non-invasive, outpatient radiosurgery, the ZAP-X platform is expected to benefit thousands of patients across India and neighbouring regions, transforming the landscape of brain tumour care and neurological treatment.

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